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Carbapenemase-producing Enterobacter spp. now Widely Distributed


A multinational study involving six countries over four continents* disclosed the increasing prevalence of Enterobacter spp. producing carbapenemase.  The study showed a common genetic structure previously identified in highly pathogenic Klebesiella pneumonia.  The epidemiologic implications from the extensive study examining isolates over the period 2008 through 2014 showed that plasmids (mobile genetic elements) expressing carbapenemase genes  move among clones and clades of Enterobacter spp. on a global scale. The authors emphasized

the need for surveillance over human populations and livestock.





*Peirano, G. et al Genomic Epidemiology of Global Carbapenemase-Producing Enterobacter spp., 2008-2014  Emerging Infectious Diseases 24: 1010-1018 (2018)